ISI Papers With Our Products

Title: Combined effects of 3D bone marrow stem cellseeded wet-electrospun poly lactic acid scaffolds on full-thickness skin wound healing
Journal: International Journal of Polymeric Materials and Polymeric Biomaterials
Author: 1. Sadegh Ghorbani, Hossein Eyni, Taki Tiraihi, Leila Salari Asl, 2. Shahram Pour Beiranvand, 3. Amir Atashi, 4,5,6. Majid Ebrahimi Warkiani
Year: 2018
Address: 1. Department of Anatomical Sciences, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran 2. Department of Hematology, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran, 3Stem Cell and Tissue Engineering Research Center, Shahroud University of Medical Sciences, Shahroud, Iran 4. School of Mechanical and Manufacturing Eng. 5. Australian Centre for Nanomedicine, University of New South Wales, Sydney, Australia, 6. Garvan Institute of Medical Research, Darlinghurst, Sydney, NSW, Australia
Abstract: Tissue engineering has emerged as an alternative treatment to traditional grafts for skin wound healing. Three-dimensional nanofibers have been used extensively for this purpose due to their excellent biomedical-related properties. In this study, high porous 3D poly lactic acid nanofibrous scaffolds (PLA-S) were prepared by wet-electrospinning technique and seeded with rat bone-marrow stem cells (BMSCs) to characterize the biocompatibility and therapeutic efficacy of these fibers on the treating full-thickness dermal wounds. The results of in vitro and in vivo studies indicate that the 3D fibrous PLA-S can be a potential wound dressing for wound repair, particularly when seeded with BMSCs.
Keywords: Wound healing, 3D nanofiber scaffold, Poly lactic acid scaffold, Skin tissue engineering, Wet electrospinning
Application: Wound Dressing, Scaffold
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URL: #http://www.tandfonline.com/doi/abs/10.1080/00914037.2017.1393681#