ISI Papers With Our Products

Title: Antibacterial and antioxidant assessment of cellulose acetate/polycaprolactone nanofibrous mats impregnated with propolis
Journal: International journal of biological macromolecules
Author: 1,2. Kamyar Khoshnevisan, Mohammad Reza Khorramizadeh, 3. Hassan Maleki, 4. Hadi Samadian, 5. Maryam Doostan,
Year: 2019
Address: 1. Biosensor Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran 2. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran 3. Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran 4. Pharmaceutical Sciences Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran 5. Department of Medical Nanotechnology, Kermanshah University of Medical Sciences, Kermanshah, Iran
Abstract: Cellulose acetate (CA) electrospun nanofibers are one of the most practical cellulosic material which normally applied as carriers for drug delivery and wound healing systems. In this study, CA and polycaprolactone (PCL) was applied to fabricate the electrospun nanofibrous for wound dressing application. Propolis is a resin-like macromolecule produced by honeybees from the buds and diverse plants. Among many applications of this macromolecule, it has been occasionally employed directly to the skin for wound healing applications. Herein, owing to the significance of propolis, CA/PCL nanofibers were impregnated with a propolis-extracted solution to reach antibacterial and antioxidant mat. The scanning electron microscopy (SEM) images revealed that electrospinning of 10% (w/w) CA along with 14% (w/w) PCL produced excellent nanofibers compared to the resultant nanofibers. Hydrophobicity/hydrophilicity nature of CA/PCL mats was measured using water contact-angle method before and after treatment with NaOH. The nanofibrous mats exhibited a high water absorption capacity of about 400%. Antioxidant effect was measured by 2,2-Diphenyl-1-picrylhydrazyl (DPPH) assay and propolis-CA/PCL presented a high antioxidant activity. Additionally, propolis-CA/PCL mats showed antibacterial activity against both the Gram-positive and Gram-negative bacteria. In conclusion, our results have confirmed that the propolis-impregnated CA/PCL mats have provided an appropriate surface for wound healing system.
Keywords: Nanofibrous mats, Propolis, Wound dressing, Electrospinning, Wound healing
Application: Wound Dressing, Antibacterial Properties
Product Model 1: Electroris
Product Model 2:
URL: #https://www.sciencedirect.com/science/article/abs/pii/S0141813019352195#